Inferring domain-domain interactions from protein-protein interactions in the complex network conformation
نویسندگان
چکیده
منابع مشابه
Inferring Domain-Domain Interactions from Protein-Protein Interactions with Formal Concept Analysis
Identifying reliable domain-domain interactions will increase our ability to predict novel protein-protein interactions, to unravel interactions in protein complexes, and thus gain more information about the function and behavior of genes. One of the challenges of identifying reliable domain-domain interactions is domain promiscuity. Promiscuous domains are domains that can occur in many domain...
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UNLABELLED The application of novel experimental techniques has generated large networks of protein-protein interactions. Frequently, important information on the structure and cellular function of protein-protein interactions can be gained from the domains of interacting proteins. We have designed a Cytoscape plugin that decomposes interacting proteins into their respective domains and compute...
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ژورنال
عنوان ژورنال: BMC Systems Biology
سال: 2012
ISSN: 1752-0509
DOI: 10.1186/1752-0509-6-s1-s7